Impact of age on the use of adjuvant treatments in patients undergoing surgery for colorectal cancer: patients with stage III colon or stage II/III rectal cancer

Autor:	C. Sarasqueta, A. Perales, A. Escobar, M. Baré, M. Redondo, N. Fernández de Larrea, E. Briones, J. M. Piera, M. V. Zunzunegui, J. M. Quintana, the REDISECC-CARESS/CCR group
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Colorectal cancer Age Equity Adherence Chemotherapy Preoperative radiotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-019-5910-z
Popis:	Abstract Background Many older patients don’t receive appropriate oncological treatment. Our aim was to analyse whether there are age differences in the use of adjuvant chemotherapy and preoperative radiotherapy in patients with colorectal cancer. Methods A prospective cohort study was conducted in 22 hospitals including 1157 patients with stage III colon or stage II/III rectal cancer who underwent surgery. Primary outcomes were the use of adjuvant chemotherapy for stage III colon cancer and preoperative radiotherapy for stage II/III rectal cancer. Generalised estimating equations were used to adjust for education, living arrangements, area deprivation, comorbidity and clinical tumour characteristics. Results In colon cancer 92% of patients aged under 65 years, 77% of those aged 65 to 80 years and 27% of those aged over 80 years received adjuvant chemotherapy (χ2 trends
Databáze:	Directory of Open Access Journals
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