Impact of e-cigarette vaping aerosol exposure in pregnancy on mTOR signaling in rat fetal hippocampus

Autor: Jehoon Lee, Marcus R. Orzabal, Vishal D. Naik, Jayanth Ramadoss
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Neuroscience, Vol 17 (2023)
Druh dokumentu: article
ISSN: 1662-453X
DOI: 10.3389/fnins.2023.1217127
Popis: Electronic cigarette (e-cig) use during pregnancy has become a major health concern in recent years and many view them as less harmful and may help quit or reduce combustible cigarettes. Implementing a state-of-the-art engineered vaping system, comprising an atomizer similar to those sold in vape shops, we aimed to utilize a translational e-cig inhalation delivery method to provide crucial information on the impact of prenatal e-cig aerosols on the developing brain hippocampal mTOR system in a rat model system. Gestational e-cig vaping significantly increased P-mTOR levels (p
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