Autor: |
Satinder Kaur, Josue Gomez-Blanco, Ahmad A. Z. Khalifa, Swathi Adinarayanan, Ruben Sanchez-Garcia, Daniel Wrapp, Jason S. McLellan, Khanh Huy Bui, Javier Vargas |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-021-21509-5 |
Popis: |
Here, the authors present two local methods for analyzing cryo-EM maps: LocSpiral and LocBSharpen that enhance high-resolution features of cryoEM maps, while preventing map distortions. They also introduce LocBFactor and LocOccupancy, which allow obtaining local B-factors and electron density occupancy maps from cryo-EM reconstructions and the authors demonstrate that these methods improve the interpretability and analysis of cryo-EM maps using different test cases among them recent SARS-CoV-2 spike glycoprotein structures. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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