Characterisation and clinical outcomes in children and adolescents with diabetes according to newly defined subgroups: a cohort study from the DPV registryResearch in context

Autor: Katharina Warncke, Alexander Eckert, Ezio Bonifacio, Peter Achenbach, Olga Kordonouri, Thomas Meissner, Ute Ohlenschläger, Walter Bonfig, Anette-G. Ziegler, Reinhard W. Holl
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: EClinicalMedicine, Vol 64, Iss , Pp 102208- (2023)
Druh dokumentu: article
ISSN: 2589-5370
DOI: 10.1016/j.eclinm.2023.102208
Popis: Summary: Background: Personalised therapy has emerged as a possibly more efficient approach taking disease heterogeneity into account. The aim of this study was to determine whether recently described subgroups of childhood diabetes have prognostic association with diabetes-specific complications and, therefore, might be a basis for personalised therapies. Methods: We applied a previously developed subgroup classification to pediatric patients (diabetes onset
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