AF2Complex predicts direct physical interactions in multimeric proteins with deep learning

Autor: Mu Gao, Davi Nakajima An, Jerry M. Parks, Jeffrey Skolnick
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29394-2
Popis: Accurate descriptions of protein-protein interactions are essential for understanding biological systems. Here the authors present AF2Complex and show that application to the E. coli cytochrome biogenesis system I yields confident computational models for three sought-after assemblies.
Databáze: Directory of Open Access Journals