| Autor: |
Lisa R Staimez, Ranjit Mohan Anjana, Viswanathan Mohan, Dorairaj Prabhakaran, Roopa Shivashankar, Dimple Kondal, Nikhil Tandon, K M Venkat Narayan, Elizabeth Selvin, Mohammed K Ali, Unjali P Gujral, Natalie Daya, Deepa Mohan, Shivani A Patel, Howard H Chang, Masood Kadir, Sayuko Kobes, Robert Hanson |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2052-4897 |
| DOI: |
10.1136/bmjdrc-2020-001988 |
| Popis: |
Introduction South Asians (SA) and Pima Indians have high prevalence of diabetes but differ markedly in body size. We hypothesize that young SA will have higher diabetes incidence than Pima Indians at comparable body mass index (BMI) levels.Research design and methods We used prospective cohort data to estimate age-specific, sex, and BMI-specific diabetes incidence in SA aged 20–44 years living in India and Pakistan from the Center for Cardiometabolic Risk Reduction in South Asia Study (n=6676), and compared with Pima Indians, from Pima Indian Study (n=1852).Results At baseline, SA were considerably less obese than Pima Indians (BMI (kg/m2): 24.4 vs 33.8; waist circumference (cm): 82.5 vs 107.0). Age-standardized diabetes incidence (cases/1000 person-years, 95% CI) was lower in SA than in Pima Indians (men: 14.2, 12.2–16.2 vs 37.3, 31.8–42.8; women: 14.8, 13.0–16.5 vs 46.1, 41.2–51.1). Risk of incident diabetes among 20–24-year-old Pima men and women was six times (relative risk (RR), 95% CI: 6.04, 3.30 to 12.0) and seven times (RR, 95% CI: 7.64, 3.73 to 18.2) higher as compared with SA men and women, respectively. In those with BMI |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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