Prevalence of Multidrug Efflux Pump Requiring Ciprofloxacin, Ofloxacin and Pefloxacin as Substrates, Among Clinical Isolates of Pseudomonas aeruginosa
Autor: | Omoregie, R., Airueghionmon, D. J. U., Okonkwo, J. O., Airueghionmon, U.– E., Ibeh, I. N., Ogefere, H. O. |
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Jazyk: | angličtina |
Rok vydání: | 2007 |
Předmět: | |
Zdroj: | Malaysian Journal of Microbiology, Vol 3, Iss 2, Pp 37-40 (2007) |
Druh dokumentu: | article |
ISSN: | 1823-8262 2231-7538 |
Popis: | Forty two consecutive clinical isolates of Pseudomonas aeruginosa were screened for the presence of reserpine inhibited multidrug (MDR) efflux pump, utilizing ciprofloxacin ofloxacin and/or pefloxacin as substrates, by determining the minimum inhibitory concentration in the presence and absence of 100 mg/L reserpine. The result showed that 50% of the Pseudomonas aeruginosa isolates possessed reserpine inhibited MDR efflux pump. MDR efflux pump requiring ofloxacin (40.48%) were significantly (p |
Databáze: | Directory of Open Access Journals |
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