Prevalence of Multidrug Efflux Pump Requiring Ciprofloxacin, Ofloxacin and Pefloxacin as Substrates, Among Clinical Isolates of Pseudomonas aeruginosa

Autor: Omoregie, R., Airueghionmon, D. J. U., Okonkwo, J. O., Airueghionmon, U.– E., Ibeh, I. N., Ogefere, H. O.
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Malaysian Journal of Microbiology, Vol 3, Iss 2, Pp 37-40 (2007)
Druh dokumentu: article
ISSN: 1823-8262
2231-7538
Popis: Forty two consecutive clinical isolates of Pseudomonas aeruginosa were screened for the presence of reserpine inhibited multidrug (MDR) efflux pump, utilizing ciprofloxacin ofloxacin and/or pefloxacin as substrates, by determining the minimum inhibitory concentration in the presence and absence of 100 mg/L reserpine. The result showed that 50% of the Pseudomonas aeruginosa isolates possessed reserpine inhibited MDR efflux pump. MDR efflux pump requiring ofloxacin (40.48%) were significantly (p
Databáze: Directory of Open Access Journals