| Autor: |
Yao Chen, Xue Ke Zhao, Rui Hua Xu, Xin Song, Miao Miao Yang, Fu You Zhou, Ling Ling Lei, Zong Min Fan, Xue Na Han, She Gan Gao, Xian Zeng Wang, Zhi Cai Liu, Ai Li Li, Wen Jun Gao, Jing Feng Hu, Li Guo Zhang, Jin Chang Wei, Fu Lin Jiao, Kan Zhong, Wei Peng Wang, Liu Yu Li, Jia Jia Ji, Xue Min Li, Li Dong Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-10 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1477-7819 |
| DOI: |
10.1186/s12957-022-02680-5 |
| Popis: |
Abstract Background This study compared the survival outcomes of different surgical approaches to determine the optimal approach for gastric cardia adenocarcinoma (GCA) and aimed to standardize the surgical treatment guidelines for GCA. Methods A total of 7103 patients with GCA were enrolled from our previously established gastric cardia and esophageal carcinoma databases. In our database, when the epicenter of the tumor was at or within 2 cm distally from the esophagogastric junction, the adenocarcinoma was considered to originate from the cardia and was considered a Siewert type 2 cancer. The main criteria for the enrolled patients included treatment with radical surgery, no radio- or chemotherapy before the operation, and detailed clinicopathological information. Follow-up was mainly performed by telephone or through home interviews. According to the medical records, the surgical approaches included transthoracic, thoracoabdominal, and transabdominal approaches. Kaplan–Meier and Cox proportional hazards regression models were applied to correlate the surgical approach with survival in patients with GCA. Results There were marked differences in age and tumor stage among the patients who underwent the three surgical approaches (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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