| Autor: |
Zhang Yibing, Zhao Yong, Ran Yongwang, Guo Jianyou, Cui Haifeng, Liu Sha |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Translational Neuroscience, Vol 11, Iss 1, Pp 215-226 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2081-6936 |
| DOI: |
10.1515/tnsci-2020-0118 |
| Popis: |
Sevoflurane, a volatile anesthetic, is known to induce widespread neuronal degeneration and apoptosis. Recently, the stress-inducible protein sestrin 2 and adenosine monophosphate-activated protein kinase (AMPK) have been found to regulate the levels of intracellular reactive oxygen species (ROS) and suppress oxidative stress. Notoginsenoside R1 (NGR1), a saponin isolated from Panax notoginseng, has been shown to exert neuroprotective effects. The effects of NGR1 against neurotoxicity induced by sevoflurane were assessed. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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