Autor: |
Fernando Bustos-Guadaño, José Luis Martín-Calderón, Juan José Criado-Álvarez, Raquel Muñoz-Jara, Adolfo Cantalejo-Gutiérrez, María Concepción Mena-Moreno |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
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Zdroj: |
Nefrología (English Edition), Vol 37, Iss 2, Pp 172-180 (2017) |
Druh dokumentu: |
article |
ISSN: |
2013-2514 |
DOI: |
10.1016/j.nefroe.2017.04.011 |
Popis: |
Background: The evidence of glomerular filtration rate (GFR) estimating with serum creatinine based formulae in the elderly population is scarce. The purpose of this study is to compare CKD-EPI, MRD4-IDMS and BIS1 equations to analyze correlation and concordance in a population older than 85 years old. Patients and methods: We designed a retrospective cross-sectional study, which included data from 600 patients older than 85 years. GFR was estimated by the following equations: CKD-EPI, MDR4-IDMS and BIS1, using as variables sex, age and serum creatinine concentration. Statistics analysis included Wilcoxon test, Bland–Altman plot, non-parametric Passing–Bablok method and kappa statistic (simple and weighted). Results: The patients’ median (range) age was 87 (interval 85–98). The median GFR (range) was 42.4 (5.2–127.4) mL/min/1.73 m2, when it was estimated with MDRD-IDMS, 40.0 (4.5–93.1) for CKD-EPI and 36.9 (7.6–83.7) for BIS1. The comparison of BIS1 and CKD-EPI and MDRD-IDMS using the Wilcoxon test was significant (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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