Metronidazole prescribing practices in Australian hospitals: Measuring guideline compliance and appropriateness to support antimicrobial stewardship

Autor: Simone Mo, Karin Thursky, Alexandros Chronas, Lisa Hall, Rodney James, Courtney Ierano
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Infection and Public Health, Vol 16, Iss , Pp 90-96 (2023)
Druh dokumentu: article
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2023.10.039
Popis: Background: Metronidazole is a commonly prescribed antimicrobial in Australian hospitals. Inappropriate use may increase risks to patient care, such as toxicities and antimicrobial resistance. To date, there is limited information on the quality of metronidazole prescriptions to inform antimicrobial stewardship and quality improvement initiatives. This study aims to describe the quality of metronidazole prescribing practices in Australian hospitals. Methods: Retrospective data analysis of the Hospital National Antimicrobial Prescribing Survey (Hospital NAPS). Data were collected by auditors at each participating hospital using a standardised auditing tool. All data from 2013 to 2021 were de-identified and analysed descriptively. Variables included were antimicrobial prescribed, indication, guideline compliance and appropriateness. Results: Metronidazole was the fifth most prescribed antimicrobial in the Hospital NAPS dataset (2013–2021), accounting for 5.7 % (n = 14,197) of all antimicrobial prescriptions (n = 250,863). The proportion of metronidazole prescriptions declined by 2 % from 2013 to 2021 (p
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