| Autor: |
Senthil Arumugam |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
BMC Biology, Vol 22, Iss 1, Pp 1-3 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1741-7007 |
| DOI: |
10.1186/s12915-023-01802-z |
| Popis: |
Organellar ion channels are regulators of key processes of cellular homeostasis as well as being involved in diseases including cancer, neurological disorders and virus infection. Individual organelle-level electrophysiology has until recently only been performed using isolated organelles, removing any direct physiological context. New DNA-based nanodevices — Clensor (chloride sensor), RatiNa (sodium sensor) and pHlicKer (potassium sensor), now allow imaging-based mapping of sodium and potassium levels in membranous organelles. This breakthrough paves the way for studying ion homeostasis relevant to a variety of diseases as well as fundamental processes. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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