The Optimization of Solvent Extraction Process from Salvia Leriifolia Leaf Extract Containing Antimicrobial Compounds Using Response Surface Methodology (RSM)

Autor: Mahbobeh Sarabi-Jamab, Mona Kaveh, Masoomeh Modarres
Jazyk: perština
Rok vydání: 2020
Předmět:
Zdroj: Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, Vol 9, Iss 2, Pp 113-126 (2020)
Druh dokumentu: article
ISSN: 2252-0937
2538-2357
DOI: 10.22101/JRIFST.2019.11.10.e1085
Popis: In this research, determining the optimal conditions for extraction of Salvia leriifolia leaf by traditional solvent extraction method (with different solvent ratio of water/ethanol 50:50, 60:40 and 70:30 at temperatures of 70, 80 and 90 ºC and time duration of 30, 75 and 120 min) in order to investigate the antimicrobial activity of the extract, using response surface method was carried out. The analysis of variances showed that the effect of all three independent variables on the dependent variables (the diameter of the inhibition zone of Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, Salmonella enteritidis, Saccharomyces cerevisiae and Aspergillus niger) was significant (p < /em>
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