Oxidant/antioxidant balance in patients with thyroid cancer
| Autor: | Melih Akinci, Funda Kosova, Bahadir Çetin, Aylin Sepici, Nilgün Altan, Sebahattin Aslan, Abdullah Çetin |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Acta Cirúrgica Brasileira, Vol 23, Iss 6, Pp 551-554 (2008) |
| Druh dokumentu: | article |
| ISSN: | 0102-8650 1678-2674 |
| DOI: | 10.1590/S0102-86502008000600013 |
| Popis: | PURPOSE: To compare the antioxidant enzyme activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and the levels of lipid peroxidation product malondialdehyde (MDA) in blood samples of thyroid cancer patients compared to healthy controls. METHODS: 43 control subjects (mean age 44±13 years) and 43 patients (43±13 years) presented with multinodular goiter whose fine needle aspiration revealed malignant cytology were included into this study. The SOD, MDA and GSH-Px activities were measured in control subjects, and before/20 days after thyroidectomy in thyroid cancer patients. RESULTS: SOD activities of pre-thyroidectomy, post-thyroidectomy and control groups were not different (p>0.05). Before thyroidectomy GSH-Px activities were lower (p |
| Databáze: | Directory of Open Access Journals |
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