Relationship between Phenotype Models Based on Waist Circumference and Triglyceride Levels and the Risk of Chronic Kidney Disease: A Systematic Review and Meta-analysis

Autor: Karunia Valeriani Japar, Timotius Ivan Hariyanto, Mochammad Sja’bani Mardjopranoto
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Obesity & Metabolic Syndrome, Vol 32, Iss 3, Pp 236-246 (2023)
Druh dokumentu: article
ISSN: 2508-6235
DOI: 10.7570/jomes23037
Popis: Background : Chronic kidney disease (CKD) is a leading cause of death worldwide and has a high cost of treatment. Studies have indicated that a combination of waist circumference (WC) and triglyceride (TG) levels can be used to determine the risk of CKD. This study analyzes the risk of CKD using four phenotype models based on WC and TG. Methods : This meta-analysis analyzes 113,019 participants from 13 studies. We conducted relevant literature searches in the Europe PMC, Medline, and Scopus databases using specific keywords. The results obtained were pooled into odds ratios (ORs) with 95% confidence intervals (CIs) using random-effects models. Results : Our pooled analysis revealed that the highest significant independent association was between CKD and the high WC-high TG phenotype (adjusted OR, 1.61; 95% CI, 1.39 to 1.88; P
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