Association between Vitamin D and Dental Caries in a Sample of Canadian and American Preschool-Aged Children

Autor: Tiffany L. Williams, Joseph Boyle, Betty-Anne Mittermuller, Caroline Carrico, Robert J. Schroth
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nutrients, Vol 13, Iss 12, p 4465 (2021)
Druh dokumentu: article
ISSN: 2072-6643
DOI: 10.3390/nu13124465
Popis: Background: Inadequate vitamin D levels may increase the risk of caries during childhood. The purpose of this study was to investigate the association between 25-hydroxyvitamin D (25(OH)D) status and severe early childhood caries (S-ECC) in preschool children. Methods: Data were obtained from children p-value of ≤0.05 was significant. Results: Data were available for 200 children with S-ECC and 144 caries-free controls. Children with S-ECC had significantly lower 25(OH)D levels than those who were caries-free (p < 0.001), and children with deficient 25(OH)D levels were 10 times more likely to have S-ECC (p < 0.001). Multiple logistic regression revealed that having higher 25(OH)D and calcium concentrations (p = 0.019 and p < 0.0001, respectively), as well as being breastfed in infancy (p < 0.001), were significantly and independently associated with lower odds of S-ECC, while dental insurance (p = 0.006) was associated with higher odds of S-ECC. Conclusions: This study provides additional evidence of an association between nutritional status, specifically vitamin D and calcium levels, and S-ECC.
Databáze: Directory of Open Access Journals