Preoperative consolidation‐to‐tumor ratio is effective in the prediction of lymph node metastasis in patients with pulmonary ground‐glass component nodules
| Autor: | Yi‐Chung Chen, Yi‐Han Lin, Hung‐Che Chien, Po‐Kuei Hsu, Jung‐Jyh Hung, Chien‐Sheng Huang, Chih‐Cheng Hsieh, Wen‐Hu Hsu, Han‐Shui Hsu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Thoracic Cancer, Vol 12, Iss 8, Pp 1203-1209 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1759-7714 1759-7706 |
| DOI: | 10.1111/1759-7714.13899 |
| Popis: | Abstract Background Preoperative positron emission tomography/computed tomography (PET/CT) is recommended as a guideline for staging of lung cancer. However, for patients with pulmonary ground‐glass opacity (GGO) nodules who are supposed to have a relatively low risk of incidence of lymphatic metastasis, it remains uncertain whether PET/CT is more effective than consolidation‐to‐tumor ratio (CTR) in the prediction of regional lymphatic metastasis. Methods The data on patients who underwent surgery for lung cancer from 2011 to 2016 were collected retrospectively, which included CTR, results of PET/CT, and pathological characteristics. The patients who had undergone preoperative PET/CT were identified to find the risk factors for lymphatic metastasis. A receiver operating characteristic (ROC) curve and multiple logistic regression was utilized to clarify the predictive value of CTR and main tumor maximal standardized uptake value (SUVmax). Results Among 217 patients who had PET/CT before lobectomy, chest computed tomography revealed that 75 patients had CTR greater than 62%. The patients with lymphatic metastasis were shown to have higher CTR and higher main tumor SUVmax. Multiple logistic regression showed that younger age ( |
| Databáze: | Directory of Open Access Journals |
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