| Autor: |
Supaschin Jamjittrong, Akihisa Matsuda, Satoshi Matsumoto, Tunyaporn Kamonvarapitak, Nobuyuki Sakurazawa, Youichi Kawano, Takeshi Yamada, Hideyuki Suzuki, Masao Miyashita, Hiroshi Yoshida |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Annals of Gastroenterological Surgery, Vol 4, Iss 1, Pp 64-75 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2475-0328 |
| DOI: |
10.1002/ags3.12300 |
| Popis: |
Abstract Aim Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used to control postoperative pain; however, their postoperative use has been associated with anastomotic leakage after gastrointestinal surgery. This systematic review and meta‐analysis aimed to determine the correlation between the use of NSAIDs and anastomotic leakage. Methods We conducted a comprehensive electronic literature search up to August 2018 to identify studies comparing anastomotic leakage in patients with and without postoperative NSAID use following gastrointestinal surgery. We then carried out a meta‐analysis using random‐effects models to calculate odds ratios (OR) with 95% confidence intervals (CI). Results Twenty‐four studies were included in this meta‐analysis, including a total of 31 877 patients. Meta‐analysis showed a significant association between NSAID use and anastomotic leakage (OR 1.73; 95% CI = 1.31‐2.29, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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