| Autor: |
Jiqiang Guo, Ying Gao, Mohammad Ahmed, Pengfei Dong, Yuping Gao, Zhihua Gong, Jinwen Liu, Yajie Mao, Zhijie Yue, Qingli Zheng, Jiansheng Li, Jianrong Rong, Yongnian Zhou, Meiwen An, Linxia Gu, Jin Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Frontiers in Pharmacology, Vol 13 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1663-9812 |
| DOI: |
10.3389/fphar.2022.816059 |
| Popis: |
Background: In stent restenosis (ISR) is one of the major complications after stent implantation. Thus, there is a growing interest in identifying a biomarker for the onset of ISR. High levels of serum homocysteine (Hcy) have been associated with the progression of cardiovascular disease. Therefore, the study was carried out to quantify the correlation between serum Hcy and ISR severity. Compared with coronary angiography (CAG), Hcy levels provided a significantly better clinical detection of ISR severity after PCI.Methods: A total of 155 patients were recruited from Shanxi Bethune hospital, from 6 months to 2 years post PCI. Serum Hcy levels and postoperative angiography results were used to differentiate the patients into two experimental groups: ISR (>50% diametrical stenosis), and non-ISR. The non-ISR included two subgroups: intimal hyperplasia (10–50% diametrical stenosis), and recovery ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
