Specific features of gastroesophageal reflux disease associated with obesity and overweight

Autor: M A Livzan, I V Lapteva, T S Krolevets, I E Kiselev
Jazyk: ruština
Rok vydání: 2016
Předmět:
Zdroj: Терапевтический архив, Vol 88, Iss 2, Pp 21-27 (2016)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
Popis: Aim. To reveal the specific features of gastroesophageal reflux disease (GERD) associated with obesity and overweight, by investigating the clinical and endoscopic manifestations of the disease, 24-hour pH-metry scores, and leptin levels. Subjects and methods. A total of 131 patients with GERD were examined. The data about complaints and those from life and medical histories were collected; anthropometric measurements and the results of blood biochemical tests, esophagoduodenoscopy (EPDS), and pH-metry were assessed; and the serum levels of leptin and its receptor were estimated. The patients were allocated into a study group (104 obese and/or overweight patients) and a comparison one (27 normal weight people). Results. Waist circumference, hip circumference, and blood glucose levels proved to be statistically significantly higher in the study group (p
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