Cytotoxicity Assessment of Copper Nanoparticles (40nm) on the Human Umbilical Vein Endothelial Cells Viability
| Autor: | Sanaz Alizadeh, Naser Aghdami, Bagher Seyed Alipour |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Vol 20, Iss 1, Pp 96-106 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1735-5338 2008-644X |
| Popis: | Abstract Background: Copper nanoparticles (Cu NPs) induced angiogenesis, has been adapted to respond the most important challenging in wound healing. But due to the toxicity of nanoparticles, the nontoxic concentrations is important. The aim of this study was to determine the concentration and size of copper nanoparticles for investigating the effect of its cytotoxicity on the endothelial cell. Materials and Methods: In this study, we exposed Cu NPs (40nm) with concentrations of 1, 10, 100 μM and 1 ,10 mM to endothelial cells and evaluate its viability effect after 24, 48 and 72 hours, according to the MTS) Methy Thiazol Tetrazolium (assay. Its optical density was determined using an ELISA reader and then was recorded. Results: The findings demonstrated that Cu NPs was significantly (p |
| Databáze: | Directory of Open Access Journals |
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