Medication history-wide association studies for pharmacovigilance of pregnant patients

Autor: Anup P. Challa, Xinnan Niu, Etoi A. Garrison, Sara L. Van Driest, Lisa M. Bastarache, Ethan S. Lippmann, Robert R. Lavieri, Jeffery A. Goldstein, David M. Aronoff
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Medicine, Vol 2, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2730-664X
DOI: 10.1038/s43856-022-00181-w
Popis: Challa et al. used 2.8 million electronic health records for proactive pharmacovigilance program development, by rapidly generating and validating hypotheses between medication use during pregnancy and neonatal neurodevelopmental defects. They identify five drug classes for which deeper safety signal evaluation may improve product marketing.
Databáze: Directory of Open Access Journals