Detection of spacer precursors formed in vivo during primed CRISPR adaptation
Autor: | Anna A. Shiriaeva, Ekaterina Savitskaya, Kirill A. Datsenko, Irina O. Vvedenskaya, Iana Fedorova, Natalia Morozova, Anastasia Metlitskaya, Anton Sabantsev, Bryce E. Nickels, Konstantin Severinov, Ekaterina Semenova |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
Druh dokumentu: | article |
ISSN: | 2041-1723 11149841 |
DOI: | 10.1038/s41467-019-12417-w |
Popis: | Primed adaptation in the CRISPR-Cas system helps recognition of previously encountered sequence elements and promotes the formation of new memories. Here the authors characterized spacer precursors of type I-E and type I-F CRISPR-Cas system using in vivo models. |
Databáze: | Directory of Open Access Journals |
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