| Autor: |
Toyin Ayofe Oyemolade, Augustine A Adeolu, Oluwakemi A Badejo, James A Balogun, Matthew T Shokunbi, Adefolarin O Malomo, Amos O Adeleye |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMJ Neurology Open, Vol 5, Iss 1 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2632-6140 |
| DOI: |
10.1136/bmjno-2022-000377 |
| Popis: |
Background Antiseizure medications, such as phenytoin sodium, have been shown in some reports to reduce the incidence of early post-traumatic seizure. These medications, however, are not without side effects which may be dose related or duration related. The risks associated with short-term therapy are minimal and often dose related (and hence avoidable). This study intends to determine the efficacy of a short-course (48-hour dose) of phenytoin in prevention of early post-traumatic seizureMethods This was a prospective randomised double-blind clinical intervention study. Head injured patients presenting within the first 24 hours were randomly assigned to either 48-hour dose of phenytoin or control groups, and were observed for clinical seizure over a week. The difference in the incidences of early post-traumatic seizure between the two groups was determined by χ2 test. A p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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