Etiological and epidemiological features of acute meningitis or encephalitis in China: a nationwide active surveillance study

Autor: Li-Ping Wang, Yang Yuan, Ying-Le Liu, Qing-Bin Lu, Lu-Sha Shi, Xiang Ren, Shi-Xia Zhou, Hai-Yang Zhang, Xiao-Ai Zhang, Xin Wang, Yi-Fei Wang, Sheng-Hong Lin, Cui-Hong Zhang, Meng-Jie Geng, Jun Li, Shi-Wen Zhao, Zhi-Gang Yi, Xiao Chen, Zuo-Sen Yang, Lei Meng, Xin-Hua Wang, Ai-Li Cui, Sheng-Jie Lai, Meng-Yang Liu, Yu-Liang Zhu, Wen-Bo Xu, Yu Chen, Zheng-Hong Yuan, Meng-Feng Li, Liu-Yu Huang, Huai-Qi Jing, Zhong-Jie Li, Wei Liu, Li-Qun Fang, Jian-Guo Wu, Simon I. Hay, Wei-Zhong Yang, George F. Gao
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: The Lancet Regional Health. Western Pacific, Vol 20, Iss , Pp 100361- (2022)
Druh dokumentu: article
ISSN: 2666-6065
DOI: 10.1016/j.lanwpc.2021.100361
Popis: Summary: Background: Acute meningitis or encephalitis (AME) results from a neurological infection causing high case fatality and severe sequelae. AME lacked comprehensive surveillance in China. Methods: Nation-wide surveillance of all-age patients with AME syndromes was conducted in 144 sentinel hospitals of 29 provinces in China. Eleven AME-causative viral and bacterial pathogens were tested with multiple diagnostic methods. Findings: Between 2009 and 2018, 20,454 AME patients were recruited for tests. Based on 9,079 patients with all-four-virus tested, 28.43% (95% CI: 27.50%‒29.36%) of them had at least one virus-positive detection. Enterovirus was the most frequently determined virus in children
Databáze: Directory of Open Access Journals