EUS-guided mucosectomy for gastrointestinal cancer Mucosectomía guiada por USE en el cáncer digestivo

Autor: J. M. Miquel, R. Abad, J. Souto, R. Fabra, M. Vila, D. Bargalló, J. L. Vázquez-Iglesias, M. J. Varas Lorenzo
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2006
Předmět:
Zdroj: Revista Espanola de Enfermedades Digestivas, Vol 98, Iss 8, Pp 582-590 (2006)
Druh dokumentu: article
ISSN: 1130-0108
Popis: Introduction: the only way of improving prognosis and survival in gastrointestinal cancer is early diagnosis, with intramucosal localization as confirmed by endoscopic ultrasonography (EUS) or 20-MHz miniprobes (MPs) (T1) being most appropriate. Endoscopic mucosal resection (EMR) has proven effective in the treatment of this sort of lesions. Patients and method: in a group (18 cases) with 15 cases of superficial gastrointestinal cancer and 3 cases of severe gastric dysplasia, 9 cases (3 esophageal, 4 gastric, 2 rectal) underwent a classic EMR following EUS or a 7.5- and 20-MHz miniprobe exploration. Results: ultrasonographic studies showed a T1 in all but one esophageal case (Tis), and in both gastric dysplasias, with no changed layer structure being demonstrated in the latter (T0). No complications arose with classic EMR, and all 9 patients are alive and free from local or metastatic recurrence, except for one esophageal case, which recurred distally to the esophageal lesion (metachronous). Conclusions: echoendoscopically-assisted EMR is a safe, effective technique in the endoscopic management of superficial gastrointestinal (esophageal, gastric, colorectal) cancer. Recurrence most likely depends upon cancer multiplicity.
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