Accuracy of Neutrophil Gelatinase-Associated Lipocalin in Detecting Acute Kidney Injury after Urogenital Robotic Assisted Laparoscopic Surgery under General Anesthesia
| Autor: | Orsolya MIHÁLY, Sorana D. BOLBOACĂ, Rodica RĂHĂIAN, Constantin BODOLEA, Cipriana CHIRA, Tudor CRISTEA, Ana OBLEZNIUC, Zoltán A. MIHÁLY, Ioan COMAN |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Applied Medical Informatics, Vol 30, Iss 2, Pp 47-56 (2012) |
| Druh dokumentu: | article |
| ISSN: | 1224-5593 2067-7855 |
| Popis: | The aim of this study was to demonstrate the accuracy of NGAL in detecting acute kidney injury (AKI) after urogenital robotic surgery in general anesthesia. Methods: A prospective longitudinal observational study, which included patients scheduled for elective robotic surgery under general anesthesia. The serum and urine NGAL at induction, 6 hours and 12 hours were determined. Serum creatinine was measured preoperatively and daily 4 days postoperatively. AKI was defined as the absolute growth of serum creatinine by 0.3 mg/dl over baseline within 48 hours postoperatively. Results: 24 patients were enrolled in the study. AKI occurred in 38% of patients. Serum NGAL increased significantly at 6 hours and 12h, compared to baseline, with a higher increase in the group of patents without AKI. There were no significant results for urine NGAL. A link was observed between the values of serum NGAL, with associated significance p |
| Databáze: | Directory of Open Access Journals |
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