Prospective analysis of cardiovascular drug intoxication

Autor: Akkan Avci, Hilmi Erdem Sümbül, Begüm Şeyda Avci, Talha Karahan, Ömer Taşkın, Yagmur Tugcan, Rana Dişel, Ayça Açıkalın, Ahmet Sebe, Mustafa Oguz Tugcan
Jazyk: English<br />Turkish
Rok vydání: 2022
Předmět:
Zdroj: Cukurova Medical Journal, Vol 47, Iss 2, Pp 835-843 (2022)
Druh dokumentu: article
ISSN: 2602-3040
DOI: 10.17826/cumj.1088964
Popis: Purpose: The aim of this study is to provide data about diagnosis, treatment, and results of the patients poisoned by drugs affecting the cardiovascular system. Materials and Methods: Patients aged 18 and over who applied to the emergency department with drug poisoning affecting cardiovasculer system were included in the study. The demographic data, drugs and doses, emergency treatment and the time of development of shock or bradycardia, treatment, antidotes and invasive procedures were recorded. Results: In our study twenty-five patients, 8 (32 %) male and 17 (68 %) female, were included. At the admission, 56 % (n=14) had hypotension, 8 % (n=2) had bradycardia, at the second hour 76 % (n=19) had hypotension, 16 % (n=4) had bradycardia. Within 6 hours after admission, 80 % (n=20) patients had hypotension, 28 % (n=7) patients had bradycardia at least once. Fifty-two percent (n=13) of the patients calcium, 36 % (n=9) glukagon, 32 % (n=8) lipid, 12 % (n=3) atropine, 20 % (n=5) positive inotropes were given. Conclusion: Lipid therapy produces positive results in patients who did not improve with calcium, glucagon and fluid therapy. Patients who received calcium channel blockers experienced more cardiogenic shock and bradycardia was more common in patients receiving beta-blockers.
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