The Effects of Ripe Pistachio Hulls Hydro-alcoholic Extract and Aerobic Training on Learning and Memory in Streptozotocin-induced Diabetic Male Rats

Autor: Sajad Abdi Gorabi, Hasan Mohammadzadeh, Mohammad Rostampour
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Basic and Clinical Neuroscience, Vol 11, Iss 4, Pp 525-534 (2020)
Druh dokumentu: article
ISSN: 2008-126X
2228-7442
Popis: Introduction: Diabetes mellitus has harmful effects on body functions, such as learning and memory. According to the role of exercise and medicinal plants on body health, the purpose of this study was to survey the effect of combined aerobic training and the use of Ripe Pistachio Hulls (RPH) hydro-alcoholic extract on learning and memory in streptozotocin-induced diabetic male rats. Methods: In this experimental study, 42 male Wistar rats weighing 250-280 g were used in 6 groups with an equal number of 7 rats in each one. Streptozotocin (STZ) (50 mg / kg)was used to induce diabetes , and the test protocol was applied for 8 weeks. Passive avoidance memory was assessed using a step-through passive avoidance apparatus (shuttle box). SPSS software was used to analyze the data and P
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