Autor: |
Ahmed Badran, Clara Steele, Hisham Alquaydheb, Ahmed Ba Theeb, Abdulmalek Bawazir, Mahmoud A. Elshenawy, Jean Paul Atallah |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Case Reports in Oncology, Vol 16, Iss 1, Pp 746-752 (2023) |
Druh dokumentu: |
article |
ISSN: |
1662-6575 |
DOI: |
10.1159/000532099 |
Popis: |
Sclerosing epithelioid fibrosarcoma is an ultra-rare and aggressive high-grade fibrosarcoma that was originally described in 1995. More than 100 cases are documented worldwide, with the most extensive case series reporting a high rate of recurrence and metastasis. ALK mutations are commonly seen in soft-tissue sarcomas; however, this is the first known case of an ALK V757M mutation. Here, we present a case using crizotinib in treating an ALK-positive sclerosing epithelioid fibrosarcoma refractory to all traditional treatment options. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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