Norepinephrine may promote the progression of Fusobacterium nucleatum related colorectal cancer via quorum sensing signalling

Autor:	Xinhao Du, Zhenzhen Tang, Li Yan, Ling Zhang, Qiao Zheng, Xianghao Zeng, Qing Hu, Qian Tian, Lanfan Liang, Xinyu Zhao, Jun Li, Ming Zhao, Xiangsheng Fu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Stress norepinephrine Fusobacterium nucleatum colorectal cancer autoinducer-2 Infectious and parasitic diseases RC109-216
Zdroj:	Virulence, Vol 15, Iss 1 (2024)
Druh dokumentu:	article
ISSN:	21505594 2150-5608 2150-5594
DOI:	10.1080/21505594.2024.2350904
Popis:	Fusobacterium nucleatum (F. nucleatum) is closely correlated with tumorigenesis in colorectal cancer (CRC). We aimed to investigate the effects of host norepinephrine on the carcinogenicity of F. nucleatum in CRC and reveal the underlying mechanism. The results revealed that both norepinephrine and bacterial quorum sensing (QS) molecule auto-inducer-2 (AI-2) were positively associated with the progression of F. nucleatum related CRC (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/c27b152f92a1451ca661149e21da73dd Zobrazit plný text záznamu View record in DOAJ