| Autor: |
Martins Otikovs, Noam Nissan, Edna Furman-Haran, Debbie Anaby, Ravit Agassi, Miri Sklair-Levy, Lucio Frydman |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Diagnostics, Vol 13, Iss 23, p 3516 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2075-4418 |
| DOI: |
10.3390/diagnostics13233516 |
| Popis: |
Quantitative correlations between T2 and ADC values were explored on cancerous breast lesions using spatiotemporally encoded (SPEN) MRI. To this end, T2 maps of patients were measured at more than one b-value, and ADC maps at several echo time values were recorded. SPEN delivered quality, artifact-free, TE-weighted DW images, from which T2-ADC correlations could be obtained despite the signal losses brought about by diffusion and relaxation. Data confirmed known aspects of breast cancer lesions, including their reduced ADC values vs. healthy tissue. Data also revealed an anticorrelation between the T2 and ADC values, when comparing regions with healthy and diseased tissues. This is contrary to expectations based on simple water restriction considerations. It is also contrary to what has been observed in a majority of porous materials and tissues. Differences between the healthy tissue of the lesion-affected breast and healthy tissue in the contralateral breast were also noticed. The potential significance of these trends is discussed, as is the potential of combining T2- and ADC-weightings to achieve an enhanced endogenous MRI contrast about the location of breast cancer lesions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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