Alemtuzumab in treatment of chronic lymphocytic leukemia
| Autor: | S. S. Bessmeltsev, E. V. Litvinskaya, K. M. Abdulkadirov, E. V. Karyagina |
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| Jazyk: | ruština |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Онкогематология, Vol 0, Iss 3, Pp 15-22 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1818-8346 2413-4023 |
| DOI: | 10.17650/1818-8346-2009-0-3-15-22 |
| Popis: | Efficiency of alemtuzumab (Campath) in 8 patients with chronic lymphocytic leukemia (CLL) was reported. Patients treated with alemtuzumab or alemtuzumab in combination with fludarabine (FluCam). Therapy response, overall survival and incidence of side effects were estimated. Among 5 patients with primary CLL, therapy response was 100%. Alemtuzumab was high effective in patients with relapsed and refractory CLL too. The main complications were myelosupression and infections. High efficacy of alemtuzumab in CLL therapy was shown. |
| Databáze: | Directory of Open Access Journals |
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