Autor: |
N. Muniyappan, M. Pandeeswaran, Augustine Amalraj |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
|
Zdroj: |
Environmental Chemistry and Ecotoxicology, Vol 3, Iss , Pp 117-124 (2021) |
Druh dokumentu: |
article |
ISSN: |
2590-1826 |
DOI: |
10.1016/j.enceco.2021.01.002 |
Popis: |
Green synthesis of gold nanoparticles (AuNPs) has garnered fervent interest due to their implicit biomedical applications. This study reveals the green synthesis of AuNPs and co-functionalization with Curcuma pseudomontana isolated curcumin (CUR). Synthesized curcumin capped nanoparticles (CUR-AuNPs) were stable and evaluated by SEM, HR-TEM, UV–vis and FT-IR spectroscopy and they were spherical in shape, homogenous with an average diameter of 20 nm along with long term stability. The CUR-AuNPs were tested for their antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli and displayed significant antibacterial activity. CUR-AuNPs showed maximum inhibition efficiency of 94% by the human red blood cell method. CUR-AuNPs also exhibited significant antioxidant and radical scavenging activities. This study sets a platform for novel synthetic AuNPs formed by utilizing reducing agents in form of isolated curcumin to effectively exploit the biomedical application of the particles. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|