Association of GHR|AluI gene polymorphism with body weight parameters in Grati-PO cattle
| Autor: | H. Hartati, A.A.R. Hapsari, B. D. P. Soewandi, S. Anwar, S. P. Rahmadani, A. Aryogi, D. Pamungkas |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Journal of the Indonesian Tropical Animal Agriculture, Vol 46, Iss 4, Pp 272-281 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2087-8273 2460-6278 |
| DOI: | 10.14710/jitaa.46.4.272-281 |
| Popis: | The growth hormone receptor (GHR) gene is member of the class I cytokine receptor family that important in growth regulation including in cattle. This study aimed to analyze the association between GHR|AluI gene with body weight, parameters in Grati-PO cattle population. A total of 304 blood samples were collected from the experimental station at the Beef Cattle Research Station, which were also equipped with 304 phenotypic data. DNA was extracted using a zymo extraction kit. Detection of of the polymorphism of GHR gene using PCR-RFLP method with AluI restriction enzymes. polymorphism indicators include genotype frequency, allele frequency, Hardy-Weinberg Equilibrium, observed heterozygosity (Ho), expected heterozygosity (He), polymorphism information content (PIC) and number of effective alleles (Ne). Association analysis was carried out using a linear mixed model. The performance of birth weight, weaning weight, yearling weight and 18 months weight were 25.4 + 0.2 kg; 113.8 + 2.3 kg; 159.9 + 2.7 kg and 213.7 + 3.6 kg, respectively. The result of association analysis was significant (P |
| Databáze: | Directory of Open Access Journals |
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