Simultaneous Multi-Slice Selective Constant-Time J-Resolved Spectroscopy for Measuring J Values

Autor: CHEN Jin-yong, ZENG Qing, LIN Yan-qin, CHEN Zhong
Jazyk: čínština
Rok vydání: 2019
Předmět:
Zdroj: Chinese Journal of Magnetic Resonance, Vol 36, Iss 04, Pp 456-462 (2019)
Druh dokumentu: article
ISSN: 1000-4556
DOI: 10.11938/cjmr20192775
Popis: Scalar coupling is an important parameter in nuclear magnetic resonance (NMR). The proton-proton coupling constant JH-H provides valuable information on molecular structure. However, determining JH-H value in complex coupling networks is still challenging. Here, we propose a method called simultaneous multi-slice selective constant-time J-resolved spectroscopy (SMS-SECTJRES) to measure JH-H values of all coupling networks of a molecule simultaneously in one experiment. In this method, gradient-encoded selective refocusing is used during a fixed evolution time, combined with echo planar spectroscopic imaging (EPSI) detection module to extract different selective J-edited spectra in different spatial positions. This new method is conducive to reveal coupling networks and the analysis of molecular structures.
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