Serum BDNF concentrations show strong seasonal variation and correlations with the amount of ambient sunlight.

Autor: Marc L Molendijk, Judith P M Haffmans, Boudewijn A A Bus, Philip Spinhoven, Brenda W J H Penninx, Jos Prickaerts, Richard C Oude Voshaar, Bernet M Elzinga
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: PLoS ONE, Vol 7, Iss 11, p e48046 (2012)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0048046
Popis: Earlier findings show seasonality in processes and behaviors such as brain plasticity and depression that in part are regulated by Brain-Derived Neurotrophic Factor (BDNF). Based on this we investigated seasonal variation in serum BDNF concentrations in 2,851 persons who took part in the Netherlands Study of Depression and Anxiety (NESDA). Analyses by month of sampling (monthly n's >196) showed pronounced seasonal variation in serum BDNF concentrations (P
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