| Autor: |
Cornelius H. L. Kürten, Aditi Kulkarni, Anthony R. Cillo, Patricia M. Santos, Anna K. Roble, Sayali Onkar, Carly Reeder, Stephan Lang, Xueer Chen, Umamaheswar Duvvuri, Seungwon Kim, Angen Liu, Tracy Tabib, Robert Lafyatis, Jian Feng, Shou-Jiang Gao, Tullia C. Bruno, Dario A. A. Vignali, Xinghua Lu, Riyue Bao, Lazar Vujanovic, Robert L. Ferris |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-27619-4 |
| Popis: |
The tumor microenvironment (TME) has an important role in Head and Neck Squamous Cell Carcinoma (HNSCC) progression. Here, using single-cell RNA sequencing and multiplexed imaging, the authors report the cellular complexity of the TME in patients with HNSCC, exploring inflammatory status, stromal heterogeneity and immune checkpoint receptor-ligand interactions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full text from SpringerLink