Ultrastructural aspects of virus replication in one fatal case and several other isolates from a dengue type 2 outbreak in Rio de Janeiro
Autor: | Ortrud Monika Barth, Luzia Monteiro de Castro Côrtes, Elisabeth Lampe, José da Costa Farias Filho |
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Jazyk: | angličtina |
Rok vydání: | 1994 |
Předmět: | |
Zdroj: | Memorias do Instituto Oswaldo Cruz, Vol 89, Iss 1, Pp 21-24 (1994) |
Druh dokumentu: | article |
ISSN: | 0074-0276 1678-8060 |
DOI: | 10.1590/S0074-02761994000100004 |
Popis: | Dengue virus replication in mosquito cell cultures was observed by electron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain. All the Brazilian isolates presented, beside the classical structured dengue virus particles, fuzzy coated virus-like particles, never observed in thereferencial New Guinea C virus strain. more numerous DEN-2 virus particles, fuzzy coated virus-like particles, defective virus particles and smooth membrane structures inside the rough endoplasmic reticulum characterized the unique fatal isolate examined. |
Databáze: | Directory of Open Access Journals |
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