| Autor: |
Guangqiang Xu, Li Zhou, Chengdong Lv, Mo Xian, Qinggang Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of Saudi Chemical Society, Vol 23, Iss 7, Pp 896-902 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1319-6103 |
| DOI: |
10.1016/j.jscs.2019.01.002 |
| Popis: |
A metal-free, acid-free, direct and eco-friendly nitration methodology has been developed. A tert-butyl nitrite efficiently promotes the direct CH nitration of electron-rich arenes with good to excellent yields and regioselectivities. The practical utility of this protocol has been demonstrated in gram-scale nitration of crown ether and mono nitration of Sesamin. A plausible free radical mechanism is proposed based on detailed experimental observations. Keywords: Metal-free, Acid-free, Tert-butyl nitrite, Nitration, Electron-rich arenes |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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