Diagnostic Dilemma of Widespread Vesiculobullous Lesions: A Case Report

Autor: Nisha Khadka, Subij Shakya, Dikshya Khatiwada, Pravash Budhathoki, Tulsi Ram Bhattarai
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Nepal Medical Association, Vol 60, Iss 245 (2022)
Druh dokumentu: article
ISSN: 0028-2715
1815-672X
DOI: 10.31729/jnma.7118
Popis: Stevens-Johnson syndrome and toxic epidermal necrolysis represent a spectrum of severe mucocutaneous reactions, while Acute Cutaneous Lupus Erythematosus is a variant of Systemic Lupus Erythematosus. Both are rare conditions, with significant morbidity and mortality; often indistinguishable clinically and pose a diagnostic dilemma for the clinician. We hereby present a unique case of a 17 years old female who presented with widespread vesiculobullous lesions with peeling, desquamation, and crusting of the skin surface, non-scarring alopecia, oral and nasal ulcers, as well as two episodes of generalized tonic-clonic seizures. The patient had a history of intake of itraconazole tablets for a week, 25 days before the disease manifestation.
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