A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection
Autor: | Hüseyin Anıl Korkmaz, Çağatay Ermiş |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | Annals of Pediatric Endocrinology & Metabolism, Vol 24, Iss 1, Pp 68-70 (2019) |
Druh dokumentu: | article |
ISSN: | 2287-1012 2287-1292 55400434 |
DOI: | 10.6065/apem.2019.24.1.68 |
Popis: | Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%–20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive. |
Databáze: | Directory of Open Access Journals |
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