A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection

Autor: Hüseyin Anıl Korkmaz, Çağatay Ermiş
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Annals of Pediatric Endocrinology & Metabolism, Vol 24, Iss 1, Pp 68-70 (2019)
Druh dokumentu: article
ISSN: 2287-1012
2287-1292
55400434
DOI: 10.6065/apem.2019.24.1.68
Popis: Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%–20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive.
Databáze: Directory of Open Access Journals