Fast forward evolution in real time: the rapid spread of SARS-CoV-2 variant of concern lineage B.1.1.7 in Saxony-Anhalt over a period of 5 months

Autor: Glaß Markus, Misiak Danny, Misiak Claudia, Müller Simon, Rausch Alexander, Angermann Katharina, Hoyer Mariann, Zabel Ramona, Kehlen Astrid, Möbius Beate, Weickert Jessica, Hüttelmaier Stefan, Karrasch Matthias
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Laboratory Medicine, Vol 46, Iss 1, Pp 71-75 (2022)
Druh dokumentu: article
ISSN: 2567-9430
2567-9449
DOI: 10.1515/labmed-2021-0092
Popis: Random mutations and recombinations are the main sources for the genetic diversity in SARS-CoV-2, with mutations in the SARS-CoV-2 spike (S) receptor binding motif (RBM) representing a high potential for the emergence of new putative variants under investigation (VUI) or variants of concern (VOC). It is of importance, to measure the different circulating SARS-CoV-2 lineages in order to establish a regional SARS-CoV-2 surveillance program. We established whole genome sequencing (WGS) of circulating SARS-CoV-2 lineages in order to establish a regional SARS-CoV-2 surveillance program.
Databáze: Directory of Open Access Journals