Plasma ceramides are associated with outcomes in acute ischemic stroke patients

Autor: Tsung-Heng Lee, Chih-Ning Cheng, Hsi-Chun Chao, Ching-Hua Lee, Ching-Hua Kuo, Sung-Chun Tang, Jiann-Shing Jeng
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of the Formosan Medical Association, Vol 121, Iss 1, Pp 43-50 (2022)
Druh dokumentu: article
ISSN: 0929-6646
12927546
DOI: 10.1016/j.jfma.2021.01.006
Popis: Background/Purpose: Sphingolipids are major constituents of eukaryotic cell membranes and play key roles in cellular regulatory processes. Our recent results in an experimental stroke animal model demonstrated changes in sphingolipids in response to acute ischemic brain injury. This study aimed to investigate the plasma levels of sphingosine-1-phosphate (S1P) and ceramides in acute ischemic stroke (AIS) patients and their associations with functional outcomes. Methods: Plasma samples were collected from patients with AIS at
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