Electrochemical miRNA Biosensors: The Benefits of Nanotechnology

Autor: Mostafa Azimzadeh, Mahdi Rahaie, Navid Nasirizadeh, Maryam Daneshpour, Hossein Naderi-Manesh
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nanomedicine Research Journal, Vol 2, Iss 1, Pp 36-48 (2017)
Druh dokumentu: article
ISSN: 2476-3489
2476-7123
DOI: 10.22034/nmrj.2017.23336
Popis: The importance of nanotechnology in medical technologies, especially biomedical diagnostics, is indubitable. By taking advantages of nanomaterials, many medical diagnostics methods have been developed so far, including electrochemical nanobiosensors. They have been used for quantification of different clinical biomarkers for detecting, screening, or follow up a disease. microRNAs (miRNAs) are one of the most recent and reliable biomarkers used for biomedical diagnosis of various diseases including different cancer types. In addition, there are many electrochemical nanobiosensors explained in publications, patents, and/or a commercial device which have been fabricated for detection or quantification of valuable miRNAs. The aim of this article is to review the concept of medical diagnostics, biosensors, electrochemical biosensors and to emphasize the role of nanotechnology in nanobiosensor development and performance for application in microRNAs detection for biomedical diagnosis. We have also summarized recent ideas and advancements in the field of electrochemical nanobiosensors for miRNA detection, and the important breakthroughs are also explained.
Databáze: Directory of Open Access Journals