Differentiation of suprasellar meningiomas from non-functioning pituitary macroadenomas by 18F-FDG and 13N-Ammonia PET/CT

Autor:	Lei Ding, Fangling Zhang, Qiao He, Zhoulei Li, Xinchong Shi, Ruocheng Li, Xiangsong Zhang
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Non-functioning pituitary macroadenoma Suprasellar meningioma 18F-FDG 13N-ammonia PET-CT Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 20, Iss 1, Pp 1-7 (2020)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-020-06852-y
Popis:	Abstract Background Differentiation of suprasellar meningiomas (SSMs) from non-functioning pituitary macroadenomas (NFPMAs) is useful for clinical management. We investigated the utility of 13N-ammonia combined with 18F-FDG positron emission tomography (PET)/computed tomography (CT) in distinguishing SSMs from NFPMAs retrospectively. Methods Fourteen NFPMA patients and eleven SSM patients with histopathologic diagnosis were included in this study. Every patient underwent both 18F-FDG and 13N-ammonia PET/CT scans. The tumor to gray matter (T/G) ratios were calculated for the evaluation of tumor uptake. Results The uptake of 18F-FDG was higher in NFPMAs than SSMs, whereas the uptake of 13N-ammonia was obviously lower in NFPMAs than SSMs. The differences of 18F-FDG and 13N-ammonia uptake between the two groups were significant respectively (0.92[0.46] vs 0.59[0.29], P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/27015c4cf901460c977dfba176b61148 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.