A Comparison of Neural Decoding Methods and Population Coding Across Thalamo-Cortical Head Direction Cells

Autor: Zishen Xu, Wei Wu, Shawn S. Winter, Max L. Mehlman, William N. Butler, Christine M. Simmons, Ryan E. Harvey, Laura E. Berkowitz, Yang Chen, Jeffrey S. Taube, Aaron A. Wilber, Benjamin J. Clark
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Frontiers in Neural Circuits, Vol 13 (2019)
Druh dokumentu: article
ISSN: 1662-5110
DOI: 10.3389/fncir.2019.00075
Popis: Head direction (HD) cells, which fire action potentials whenever an animal points its head in a particular direction, are thought to subserve the animal’s sense of spatial orientation. HD cells are found prominently in several thalamo-cortical regions including anterior thalamic nuclei, postsubiculum, medial entorhinal cortex, parasubiculum, and the parietal cortex. While a number of methods in neural decoding have been developed to assess the dynamics of spatial signals within thalamo-cortical regions, studies conducting a quantitative comparison of machine learning and statistical model-based decoding methods on HD cell activity are currently lacking. Here, we compare statistical model-based and machine learning approaches by assessing decoding accuracy and evaluate variables that contribute to population coding across thalamo-cortical HD cells.
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