Chronic nerve health following implantation of femoral nerve cuff electrodes

Autor: Max J. Freeberg, Gilles C. J. Pinault, Dustin J. Tyler, Ronald J. Triolo, Rahila Ansari
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of NeuroEngineering and Rehabilitation, Vol 17, Iss 1, Pp 1-17 (2020)
Druh dokumentu: article
ISSN: 1743-0003
DOI: 10.1186/s12984-020-00720-3
Popis: Abstract Background Peripheral nerve stimulation with implanted nerve cuff electrodes can restore standing, stepping and other functions to individuals with spinal cord injury (SCI). We performed the first study to evaluate the clinical electrodiagnostic changes due to electrode implantation acutely, chronic presence on the nerve peri- and post-operatively, and long-term delivery of electrical stimulation. Methods A man with bilateral lower extremity paralysis secondary to cervical SCI sustained 5 years prior to enrollment received an implanted standing neuroprosthesis including composite flat interface nerve electrodes (C-FINEs) electrodes implanted around the proximal femoral nerves near the inguinal ligaments. Electromyography quantified neurophysiology preoperatively, intraoperatively, and through 1 year postoperatively. Stimulation charge thresholds, evoked knee extension moments, and weight distribution during standing quantified neuroprosthesis function over the same interval. Results Femoral compound motor unit action potentials increased 31% in amplitude and 34% in area while evoked knee extension moments increased significantly (p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje