Where do you live? North versus Central-South differences in relation to Italian patients with oral lichen planus: a cross-sectional study from the SIPMO (Italian Society of Oral Pathology and Medicine)

Autor: Daniela Adamo, Elena Calabria, Federica Canfora, Noemi Coppola, Lorenzo Lo Muzio, Francesca Spirito, Michele Giuliani, Lorenzo Azzi, Vittorio Maurino, Giuseppe Colella, Chiara Colella, Lucio Montebugnoli, Davide Bartolomeo Gissi, Mario Gabriele, Marco Nisi, Andrea Sardella, Giovanni Lodi, Elena Maria Varoni, Amerigo Giudice, Alessandro Antonelli, Paolo Giacomo Arduino, Alessio Gambino, Paolo Vescovi, Alessandra Majorana, Elena Bardellini, Giuseppina Campisi, Vera Panzarella, Francesco Spadari, Umberto Garagiola, Monica Pentenero, Samuele Sutera, Matteo Biasotto, Giulia Ottaviani, Margherita Gobbo, Luca Guarda Nardini, Umberto Romeo, Gianluca Tenore, Rosario Serpico, Alberta Lucchese, Carlo Lajolo, Cosimo Rupe, Massimo Aria, Luca D’Aniello, Michele Davide Mignogna, SIPMO (Italian Society of Oral Pathology and Medicine)
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Oral Health, Vol 22, Iss 1, Pp 1-16 (2022)
Druh dokumentu: article
ISSN: 1472-6831
DOI: 10.1186/s12903-022-02181-7
Popis: Abstract Background Oral lichen planus (OLP) is an immune-mediated inflammatory chronic disease of the oral mucosa, with different patterns of clinical manifestations which range from keratotic manifestations (K-OLP) to predominantly non-keratotic lesions (nK-OLP). The aim of the study was to analyze the differences in the clinical, psychological profile and symptoms between Italian patients of the North and Central-South with K-OLP and nK-OLP. Methods 270 K-OLP and 270 nK-OLP patients were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale (ESS) were administered. Results The Central-South K-OLP (CS-K-OLP) patients reported a higher frequency of pain/burning compared with the K-OLP patients of the North (N-K-OLP) with higher scores in the NRS and T-PRI (p value
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