Norethindrone is superior to combined oral contraceptive pills in short-term delay of menses and onset of breakthrough bleeding: a randomized trial

Autor:	Joshua Dean, Katherine J. Kramer, Fauzia Akbary, Shaunte Wade, Maik Hüttemann, Jay M. Berman, Maurice-Andre Recanati
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Norethindrone Menstruation delay Randomized controlled study Vaginal bleeding Gynecology and obstetrics RG1-991 Public aspects of medicine RA1-1270
Zdroj:	BMC Women's Health, Vol 19, Iss 1, Pp 1-9 (2019)
Druh dokumentu:	article
ISSN:	1472-6874
DOI:	10.1186/s12905-019-0766-6
Popis:	Abstract Background To determine whether oral norethindrone acetate is superior to combined oral contraceptives (OCP) in delaying menstruation and preventing breakthrough bleeding when started late in the cycle. Methods This article comprises of a case control study followed by a pilot randomized controlled study. In the first study, four women who presented late in their cycle and desired avoiding vaginal bleeding within 10 days before a wedding were started on norethindrone 5 mg three times daily and compared to age matched controls started on OCPs. Subsequently, a randomized controlled pilot study (n = 50) comparing OCPs to norethindrone for the retiming of menses was conducted. Percentage of women reporting spotting were compared with level of statistical significance set at p
Databáze:	Directory of Open Access Journals
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